Mechanisims of asthma and allergic disease – 1070. Genetic mechanisms of immune imbalance in allergic inflamation

Background At the present time is considered an established fact that at every stage of the immunological response to free radicals and their derivatives, antioxidant enzymes perform a regulatory function and may help limit or activation of immune responses. In this regard, of interest to identify the functionally significant variant genotype polymorphism Ile-105/Val-105 GSTπ1, which can contribute to and interfere with the functioning of the immune system in allergic diseases.